CRLF2 anticorps

N° du produit ABIN7193712

Cet anticorps anti-CRLF2 est un anticorps Souris Monoclonal détectant CRLF2 dans ELISA, IHC et FACS. Adapté pour Humain.

Aperçu rapide pour CRLF2 anticorps (ABIN7193712)

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRLF2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1E10D3

Détail du produit anti-CRLF2 anticorps

Fonction: TSLPR Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human TSLPR (AA: extra(23-231)) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CRLF2

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Autre désignation: TSLPR

Sujet:

This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 42 kDa